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    Do you distribute, re-sell or sell wholesale products? If you do, you will soon encounter what may be your
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    biggest opportunity for success… or failure. A large order from your best customer. A large order that ex
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ceeds your current financing capabilities. If you deliver it successfully, you can count on taking your co
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    pany to the next level. If you don’t, your competitors will be the ones that eat your lunch and take their
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    business to the next level

    So, how do you handle an order that is too large for your business? You finan
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ce it. How? Using purchase order financing.

    Let’s look at how things work in your business right now. Eve
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    y time you get a purchase order from a client you go ahead and order the product from your suppliers. You
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    either pay your supplier upfront or using bank financing. The supplier delivers the product and then your
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    client pays you 30 or 60 days later.

    However if you don’t have enough money to pay your supplier, the who
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    e transaction falls through. Purchase order financing can provide you with up to 100% of the funds needed
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    to pay your suppliers and make the sale.

    There are only three major requirements to qualify for purchase
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    order financing:

    1. You must have a purchase order from a large credit worthy commercial customer

    2. You
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    supplier must drop ship items directly to your customer

    3. Your sales must be final (e.g. no guaranteed
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    sales or consignment)

    If you meet these three criteria, you have a very good chance of qualifying for pur
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    chase order financing. Purchase order financing works as follows:

    1. You get a large purchase order from
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    client

    2. The purchase order financing company issues a payment guarantee to your suppliers (usually thr
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ough a letter of credit)

    3. Your supplier drop ships the order and you issue an invoice

    4. Once your cli
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ent pays the invoice, the transaction is settled

    With purchase order financing, your sales capabilities w
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ll no longer be limited by your financial strength. You can sell as much as you can finance. And – if your
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    clients are credit worthy and good payers –you can finance as much as you want, the sky will be the limit


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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